تفاعل #531790

معادلة التفاعل

Mercaptopropionic acid

Triphenylmethylchloride

→

3-(tritylthio)propanoic acid

المردود 95.7%

3-(tritylthio) propanoic acid

المردود 95.7%

المذيبات

methylene chloride

ظروف التفاعل

المعالجة

1. 1
   أخرىwere carried out at room temperature
2. 2
   ترشيحwas filtered
3. 3
   غسيلwas rinsed with 40 ml of diethyl ether
4. 4
   أخرىThe precipitate was then dried under reduced pressure

الإجراء التجريبي

Mercaptopropionic acid 2 (3.14 g) was dissolved in 50 ml of methylene chloride. Triphenylmethylchloride 3 (8.36 g, 30 mmol) was added to that, and 19-hour protection reactions were carried out at room temperature. The precipitate generated through the protection reactions was filtered and gathered, and was rinsed with 40 ml of diethyl ether. The precipitate was then dried under reduced pressure, to form 9.86 g of 3-(tritylthio)propanoic acid 4, which is a white solid.

المصدر