تفاعل #53081

ord-45eebfcfaf5042ff9a9bd22062456481

معادلة التفاعل

COC(=C1C(=O)N(C(=O)c2ccccc2)c2ccc([N+](=O)[O-])cc21)c1ccccc1
1-benzoyl-3-(1-methoxy-1-phenyl-methylidene)-5-nitro-2-indolinone
N#Cc1ccc(N)cc1
4-aminobenzonitrile
N
ammonia
→
N#Cc1ccc(N/C(=C2\C(=O)Nc3ccc([N+](=O)[O-])cc32)c2ccccc2)cc1
(Z)-3-[1-(4-cyanophenylamino)-1-phenyl-methylidene]-5-nitro-2-indolinone

المتفاعلات

COC(=C1C(=O)N(C(=O)c2ccccc2)c2ccc([N+](=O)[O-])cc21)c1ccccc1
1-benzoyl-3-(1-methoxy-1-phenyl-methylidene)-5-nitro-2-indolinone
N#Cc1ccc(N)cc1
4-aminobenzonitrile
N
ammonia

الكواشف

لا شيء

المذيبات

CN(C)C=O
DMF

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

Prepared analogously to Example 77 from 1-benzoyl-3-(1-methoxy-1-phenyl-methylidene)-5-nitro-2-indolinone and 4-aminobenzonitrile in DMF and subsequent treatment with methanolic ammonia.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US06855710B2uspto-grants-2005_02