تفاعل #53057

ord-c0d95bc40a6d440cb231222a1bec02b3

معادلة التفاعل

CCOC(=C1C(=O)N(C(C)=O)c2ccccc21)c1ccccc1
1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-2-indolinone
N#Cc1ccc(N)cc1
4-aminobenzonitrile
[Na+].[OH-]
sodium hydroxide
→
N#Cc1ccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)cc1
(Z)-3-[1-(4-cyanophenylamino)-1-phenyl-methylidene]-2-indolinone

المتفاعلات

CCOC(=C1C(=O)N(C(C)=O)c2ccccc21)c1ccccc1
1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-2-indolinone
N#Cc1ccc(N)cc1
4-aminobenzonitrile
[Na+].[OH-]
sodium hydroxide

الكواشف

لا شيء

المذيبات

CN(C)C=O
DMF

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

Prepared analogously to Example 1 from 1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-2-indolinone and 4-aminobenzonitrile in DMF and subsequent treatment with sodium hydroxide solution.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US06855710B2uspto-grants-2005_02