تفاعل #53049

معادلة التفاعل

N-bromoacetyl-4-nitro-aniline

morpholine

potassium carbonate

→

N-morpholinomethylcarbonyl-4-nitroaniline

المذيبات

acetone

acetone

ظروف التفاعل

المعالجة

1. 1
   workup.ADDITIONare added dropwise over a period of 20 minutes
2. 2
   ترشيحThe precipitate is filtered off
3. 3
   ترشيحfiltered
4. 4
   أخرىdried in a drying cupboard

الإجراء التجريبي

2.6 g (30 mmol) of morpholine and 4.2 g (30 mmol) of potassium carbonate are suspended in 120 ml of acetone. 5.3 g (20 mmol) of N-bromoacetyl-4-nitro-aniline, dissolved in 80 ml of acetone, are added dropwise over a period of 20 minutes and then stirred for 2 hours at ambient temperature. The precipitate is filtered off and the solvent is eliminated in vacuo. The residue is suspended with water. The precipitate is suction filtered and dried in a drying cupboard.

المصدر