تفاعل #53009

ord-07754e2c305845f0ad29ee868a609ebb

معادلة التفاعل

CCOC(=C1C(=O)N(C(C)=O)c2ccccc21)c1ccccc1
1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-2-indolinone
COc1ccccc1N
2-methoxyaniline
[Na+].[OH-]
sodium hydroxide
→
COc1ccccc1N/C(=C1\C(=O)Nc2ccccc21)c1ccccc1
(Z)-3-[1-(2-methoxy-phenylamino)-1-phenyl-methylidene]-2-indolinone

المتفاعلات

CCOC(=C1C(=O)N(C(C)=O)c2ccccc21)c1ccccc1
1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-2-indolinone
COc1ccccc1N
2-methoxyaniline
[Na+].[OH-]
sodium hydroxide

الكواشف

لا شيء

المذيبات

CN(C)C=O
DMF
CO
methanol

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

Prepared analogously to Example 1 from 1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-2-indolinone and 2-methoxyaniline in DMF and subsequent treatment with sodium hydroxide solution in methanol.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US06855710B2uspto-grants-2005_02