تفاعل #529778

معادلة التفاعل

4,4'-Diphenol

triethylamine

Nonanoyl chloride

dimethylpyridine

→

titled compound

المردود 159.7%

4-n-Nonanoyloxy-4'-hydroxybiphenyl

المردود 159.7%

المذيبات

dichloromethane

ظروف التفاعل

المعالجة

1. 1
   استخلاصsubjected to extraction with dichloromethane
2. 2
   تجفيفThe organic layer was dried over anhydrous magnesium sulfate
3. 3
   أخرىremoved by evaporation
4. 4
   أخرىto give a crude product
5. 5
   أخرىIt was purified by silica gel column chromatography (developer: hexane/ethyl acetate=3/2)

الإجراء التجريبي

4,4'-Diphenol (0.1 g) and triethylamine (0.57 g) were dissolved in dichloromethane (20 ml). Nonanoyl chloride (1.0 g) and dimethylpyridine (0.2 g) were added thereto, and the mixture was stirred at room temperature for about 20 hours. The reaction mixture was poured into ice-water and subjected to extraction with dichloromethane. The organic layer was dried over anhydrous magnesium sulfate and removed by evaporation to give a crude product. It was purified by silica gel column chromatography (developer: hexane/ethyl acetate=3/2) to give the titled compound (0.28 g).

المصدر