تفاعل #529776

معادلة التفاعل

hydrochloric acid

Nonanoyl chloride

dimethylaminopyridine

4'-Hydroxybiphenyl-4-carboxylic acid

→

titled compound

المردود 86.3%

4'-n-nonanoyloxybiphenyl-4-carboxylic acid

المردود 86.3%

المذيبات

dichloromethane

triethylamine

ظروف التفاعل

المعالجة

1. 1
   أخرىthe organic layer was separated in a separating funnel
2. 2
   أخرىThe solvent was removed by evaportaion
3. 3
   أخرىthe residue was dried
4. 4
   غسيلafter washing with n-hexane

الإجراء التجريبي

4'-Hydroxybiphenyl-4-carboxylic acid (3.5 g) and triethylamine (2.4 g) were dissolved in dichloromethane (30 ml). Nonanoyl chloride (4.3 g) and dimethylaminopyridine (0.2 g) were added to the solution, and the mixture was stirred at room temperature for about 20 hours. Dilute hydrochloric acid was added thereto, and the organic layer was separated in a separating funnel. The solvent was removed by evaportaion, and the residue was dried after washing with n-hexane to give the titled compound (5 g).

المصدر