تفاعل #52307

معادلة التفاعل

sodium hydroxide

trimethyl-triethoxyprop-1-ynyl-silane

→

title compound

المردود 55.8%

3,3,3-Triethoxypropyne

المردود 55.8%

المذيبات

water

ethanol

water

ظروف التفاعل

المعالجة

1. 1
   استخلاصthe mixture was extracted with ethyl acetate
2. 2
   تجفيفThe organic extracts were dried with magnesium sulfate
3. 3
   أخرىthe solvent was removed under reduced pressure

الإجراء التجريبي

A solution of sodium hydroxide (0.14 g, 3.60 mmol) in water (50 mL) was added to a solution of trimethyl-triethoxyprop-1-ynyl-silane (50.0 g, 208 mmol) in ethanol (250 mL). After stirring for 1 hour at room temperature, water was added and the mixture was extracted with ethyl acetate. The organic extracts were dried with magnesium sulfate and the solvent was removed under reduced pressure to give the title compound (20.0 g, 52% yield) as yellow oil. 1H NMR (CDCl3) δ 3.70 (q, 6H, J=8.0 Hz), 2.56 (s, 1H) 1.24 (t, 9H, J=8.0 Hz).

المصدر