تفاعل #51934
ord-212bfc66156440dcb496d984dc7e2eed
معادلة التفاعل
ظروف التفاعل
الظروف التفصيلية
See reaction.notes.procedure_details.
المعالجة
- 1درجة الحرارةrefluxed for 4 h
- 2درجة الحرارةcooled
- 3ترشيحfiltered
- 4غسيلThe organic phase is washed with brine
- 5تجفيفdried (MgSO4)
- 6تركيزconcentrated under reduced pressure
الإجراء التجريبي
To a stirred solution of 1.32 g of 3-[2-(2-methoxyethoxy)ethoxy]benzaldehyde and 15 mg of tetra-n-butylammonium bromide in 15 ml of CH2Cl2 is added a solution of 2.4 g of trimethylsulfonium methylsulfate in 4 ml of water, followed by 10 ml of 50% NaOH. The mixture is stirred and refluxed for 4 h, then cooled, diluted with ether and brine, and filtered. The organic phase is washed with brine, dried (MgSO4), and concentrated under reduced pressure to provide 1.78 g of the title compound as a pale yellow oil.