تفاعل #516929

معادلة التفاعل

N-benzyloxycarbonyl glycine

tetradecylalcohol

DCC

→

N-benzyloxycarbonylglycine tetradecyl ester

المردود 59.7%

المذيبات

ethyl acetate

ظروف التفاعل

المعالجة

1. 1
   أخرىAfter the precipitation which
2. 2
   ترشيحappeared was filtered off
3. 3
   تركيزthe filtrate was concentrated in vacuo
4. 4
   غسيلThe residue was washed with ethanol

الإجراء التجريبي

To a solution of N-benzyloxycarbonyl glycine (3 g, 14.3 mmol), tetradecylalcohol (3.07 g, 14.3 mmol) an N,N-dimethylaminopyridine (87 mg, 10.3 mmol) in ethyl acetate (100 ml) was added DCC (2.98 g, 2.34 mmol) and the resulting mixture was stirred for 2 h at room temperature. After the precipitation which appeared was filtered off, the filtrate was concentrated in vacuo. The residue was washed with ethanol to give N-benzyloxycarbonylglycine tetradecyl ester (7) (3.46 g, 59.5%) as crystal.

المصدر