تفاعل #508095

معادلة التفاعل

2-carboxymethyl-1-(4-carboxymethyl-phenyl)-5-hydroxyindole-3-carboxylic acid ethyl ester

2-Carboxymethyl-1-(4-carboxymethylphenyl)-5-hydroxyindole-3-carboxylic acid ethyl ester

4-trifluoromethylphenylboronic acid

→

sub-title compound

2-Carboxymethyl-1-(4-carboxymethylphenyl)-5-(4-trifluoromethylphenoxy)indole-3-carboxylic acid ethyl ester

ظروف التفاعل

الإجراء التجريبي

The sub-title compound was prepared in accordance with step (c) Example 1 from 2-carboxymethyl-1-(4-carboxymethyl-phenyl)-5-hydroxyindole-3-carboxylic acid ethyl ester (235 mg, 0.5 mmol, see step (b) Example 7) and 4-trifluoromethylphenylboronic acid (143 mg, 0.75 mmol). Yield 122 mg, 41%.

المصدر