تفاعل #50654

ord-13ffca73d3c24e7889743ce81264ae5a

معادلة التفاعل

O=C(c1ccccc1)c1cc[nH]c1
3-benzoylpyrrole
NOS(=O)(=O)O
hydroxylamine-O-sulfonic acid
Nn1ccc(C(=O)c2ccccc2)c1
1-amino-3-benzoylpyrrole

الكواشف

لا شيء

المذيبات

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

A 3-benzoylpyrrole of the formula ##STR25## in potassium hydroxide or other suitable base is reacted with hydroxylamine-O-sulfonic acid to yield a 1-amino-3-benzoylpyrrole of the formula ##STR26## This reaction typically takes place in the presence of a suitable solvent such as dimethylformamide at a temperature of about 0° to 25° C. (or at room temperature) for 0.5 to 4 hours.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US05428053uspto-grants-1995_06