تفاعل #50375

معادلة التفاعل

hydrochloric acid

sodium hydride

methyl isoferulate

glycidol

→

cinnamic acid

المذيبات

DMSO

ظروف التفاعل

المعالجة

1. 1
   workup.ADDITIONwas added gradually
2. 2
   درجة الحرارةHeating
3. 3
   درجة الحرارةThe system was cooled
4. 4
   أخرىwas removed

الإجراء التجريبي

3 g of methyl isoferulate was dissolved in 600 ml of DMSO, and 370 mg of sodium hydride was added. The system was heated to 90° C. under N2 gas flow and 7 g of glycidol was added gradually. Heating and agitation was carried out for 0.5 hours. The system was cooled, neutralized by adding hydrochloric acid, solvent was removed and adduct of cinnamic acid and glycerin was obtained.

المصدر