تفاعل #50259

معادلة التفاعل

10-Mercaptomethyl-3-t-butoxycarbonylmethyl-2-oxo-1-azacyclodecane

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10-mercaptomethyl-2-oxo-1-azacyclodecane-3-acetic acid

المذيبات

methylene chloride

ظروف التفاعل

المعالجة

1. 1
   أخرىGaseous hydrogen chloride is bubbled through the solvent for 15 minutes
2. 2
   أخرىthe reaction is sealed
3. 3
   أخرىThe solvent is evaporated the next day

الإجراء التجريبي

10-Mercaptomethyl-3-t-butoxycarbonylmethyl-2-oxo-1-azacyclodecane (0.21 g, 0.69 mmol) is dissolved in methylene chloride (15 mL). Gaseous hydrogen chloride is bubbled through the solvent for 15 minutes, and then the reaction is sealed and stirred overnight. The solvent is evaporated the next day to give 10-mercaptomethyl-2-oxo-1-azacyclodecane-3-acetic acid, MS: M+1=260.

المصدر