تفاعل #502097

معادلة التفاعل

sodium borohydride

5-[2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl]furan-2-carbaldehyde

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compound

المردود 37.3%

{5-[2-(4-Chlorophenyl)imidazo[1,2-a]pyridin-6-yl]furan-2-yl}methanol

المردود 37.3%

المذيبات

methanol

ظروف التفاعل

المعالجة

1. 1
   أخرىthe solvent is then evaporated off under reduced pressure
2. 2
   أخرىThe organic phase is separated
3. 3
   تجفيفdried over sodium sulphate
4. 4
   تركيزconcentrated under reduced pressure

الإجراء التجريبي

122 mg of sodium borohydride are added, in small portions, to 104 mg of 5-[2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl]furan-2-carbaldehyde dissolved in 20 ml of methanol. The mixture is subsequently stirred at ambient temperature for 2 hours, and the solvent is then evaporated off under reduced pressure. The residue is taken up between dichloromethane and water. The organic phase is separated, dried over sodium sulphate and concentrated under reduced pressure. 39 mg of compound are obtained.

المصدر