تفاعل #5004

معادلة التفاعل

methyl 2-acetyl-6-[(4,6-dimethoxytriazin-2-yl)oxy]benzoate

methoxyamine hydrochloride

potassium acetate

methanol

→

aimed compound

المردود 48.0%

methyl 2-[(4,6-dimethoxytriazin-2-y1)oxy]-6-[1-(N-methoxyimino)ethyl]benzoate

المردود 48.0%

المذيبات

water

ظروف التفاعل

المعالجة

1. 1
   أخرىThe resultant reaction liquor
2. 2
   استخلاصwas extracted with ethyl acetate
3. 3
   غسيلAfter washing the extracted product with water
4. 4
   أخرىthe washed product was dried
5. 5
   تركيزconcentrated
6. 6
   أخرىto obtain an oily product
7. 7
   أخرىThis was then purified by column chromatography

الإجراء التجريبي

0.9 of methyl 2-acetyl-6-[(4,6-dimethoxytriazin-2-yl)oxy]benzoate, 0.68 g of methoxyamine hydrochloride and 0.80 g of potassium acetate were added to 30 ml of methanol, and the resultant mixture was stirred for one day and one night at room temperature. The resultant reaction liquor was poured into water, and was extracted with ethyl acetate. After washing the extracted product with water, the washed product was dried and concentrated to obtain an oily product. This was then purified by column chromatography to obtain 0.47 g of the aimed compound (melting point=131° to 135° C.) at a yield of 48%.

المصدر