تفاعل #496147

معادلة التفاعل

Phosphorus oxychloride

2-methylnaphthalen-1-ol

triethylamine

→

2-Methylnaphthalen-1-yl phosphorodichloridate

المذيبات

diethyl ether

ظروف التفاعل

المعالجة

1. 1
   أخرىwas very unstable at room temperature

الإجراء التجريبي

Phosphorus oxychloride (0.176 mL, 1 equiv) and 2-methylnaphthalen-1-ol (Aldrich, 0.3 g, 1 equiv) were stirred in anhydrous diethyl ether (10 mL). Anhydrous triethylamine was added (0.264 mL, 1 equiv) at −78° C. and stirred for 30 min. The dichloridate was very unstable at room temperature. The progress of the reaction was monitored by 31P NMR. This crude mixture was considered to be a 100% conversion to dichloridate and was used directly.

المصدر