تفاعل #491933

ord-6443278dd5cc4b8aaaf27b3ec2a160e6

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    أخرىcould be obtained

الإجراء التجريبي

Starting from 7-Bromo-6-chloroisoquinoline (265) and 3-Bromomethyl-pyrrolidine-1-carboxylic acid tert-butyl ester 7-Bromo-6-(pyrrolidin-3-ylmethylsulfanyl)-isoquinoline could be obtained according to the procedures described for 272, 267, 268 as the hydrochloride. Rt=0.72 min (Method B). Detected mass: 323.1/325.2 (M+H+).

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US08748614B2uspto-grants-2014_06