تفاعل #49078

معادلة التفاعل

D1

1-(dimethylamino)cyclopentanecarbonitrile

dimethylamine hydrochloride

3-pentanone

potassium cyanide

→

title compound

المردود 57.5%

2-(Dimethylamino)-2-ethylbutanenitrile

المردود 57.5%

المذيبات

water

ظروف التفاعل

الإجراء التجريبي

The title compound (8.05 g, 57.5%) was prepared from dimethylamine hydrochloride (8.154 g, 0.1 mol), 3-pentanone (8.61 g, 0.1 mol) and potassium cyanide (6.51 g, 0.1 mol) in water (50 ml) in a similar manner to that described in D1. 1H NMR (CDCl3) δ: 0.96 (6H, t, J=7.6 Hz), 1.67-1.90 (4H, m), 2.33 (6H, s).

المصدر