تفاعل #490261
ord-008e53fed2d347c69c94dd5dff300c10
معادلة التفاعل
الكواشف
لا شيء
ظروف التفاعل
درجة الحرارة
130°CELSIUS
الظروف التفصيلية
See reaction.notes.procedure_details.
المعالجة
- 1أخرىto remove hydrogen chloride
- 2أخرىproduced as a by-product
الإجراء التجريبي
A 30.0 g quantity of N-methoxymethyl-N-methylpyrrolidinium chloride prepared in Example 10 was dissolved in 30.0 g of MeOH, and 80.0 g of methanol solution of 35 wt. % trifluoromethanesulfonic acid was added to the solution. The mixture was heated at 130° C. in a nitrogen stream to remove hydrogen chloride produced as a by-product, an excess of trifluoromethanesulfonic acid and methanol, giving 49.0 g of the desired product.