تفاعل #490260

معادلة التفاعل

sodium acetate

N-methoxymethyl-N-methylpyrrolidinium chloride

N-methyl-N-methoxymethylpyrrolidinium chloride

→

desired product

N-methoxymethyl-N-methylpyrrolidinium acetate

المذيبات

methanol

ظروف التفاعل

المعالجة

1. 1
   أخرىThe mixture was reacted at room temperature for 1.5 hours
2. 2
   أخرىwhereby the reaction was terminated
3. 3
   ترشيحThe reaction mixture was filtered
4. 4
   تركيزthe filtrate was concentrated
5. 5
   أخرىdried in a vacuum
6. 6
   workup.ADDITIONTo the residue was added 100 ml of dichloromethane
7. 7
   ترشيحfollowed by filtration with a membrane
8. 8
   ترشيحfilter
9. 9
   تركيزconcentration in a vacuum
10. 10
    أخرىdrying

الإجراء التجريبي

A 9.46 g quantity of sodium acetate (product of Wako Pure Chemical Ind. Ltd.) was dissolved in 95 g of methanol, and 19.10 g of N-methoxymethyl-N-methylpyrrolidinium chloride was added to the solution. The mixture was reacted at room temperature for 1.5 hours, whereby the reaction was terminated. The reaction mixture was filtered, and the filtrate was concentrated and dried in a vacuum. To the residue was added 100 ml of dichloromethane, followed by filtration with a membrane filter, concentration in a vacuum and drying, affording 20.38 g of the desired product.

المصدر