تفاعل #490256

معادلة التفاعل

sodium carbonate

N-methoxymethyl-N-methylpyrrolidinium chloride

N-methyl-N-methoxymethylpyrrolidinium chloride

→

desired product

N-methoxymethyl-N-methylpyrrolidinium carbonate

المذيبات

water

ظروف التفاعل

المعالجة

1. 1
   أخرىThe mixture was reacted at room temperature for 0.5 hour
2. 2
   أخرىwhereby the reaction was terminated
3. 3
   تركيزThe reaction mixture was concentrated
4. 4
   تجفيفdried in vacuum, and 100 ml of ethyl alcohol
5. 5
   workup.ADDITIONwas added to the residue
6. 6
   أخرىto remove insoluble sodium chloride
7. 7
   workup.DISSOLUTIONThe resulting product was dissolved in dichloromethane
8. 8
   ترشيحthe solution was filtered with a membrane
9. 9
   ترشيحfilter again
10. 10
    تركيزthe filtrate was concentrated in a vacuum
11. 11
    أخرىdried

الإجراء التجريبي

A 1.60 g quantity of sodium carbonate (product of Wako Pure Chemical Ind. Ltd.) was dissolved in 18 g of deionized water, and 5.01 g of N-methoxymethyl-N-methylpyrrolidinium chloride was added to the solution. The mixture was reacted at room temperature for 0.5 hour, whereby the reaction was terminated. The reaction mixture was concentrated and dried in vacuum, and 100 ml of ethyl alcohol was added to the residue to remove insoluble sodium chloride. The resulting product was dissolved in dichloromethane, the solution was filtered with a membrane filter again, and the filtrate was concentrated in a vacuum and dried, giving 5.41 g of the desired product.

المصدر