تفاعل #487648

معادلة التفاعل

(7-benzyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-2-yl)-phenyl-amine

hydrogen

→

desired product

المردود 77.0%

phenyl-(6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-2-yl)-amine

المردود 77.0%

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe mixture was filtered
2. 2
   أخرىevaporated

الإجراء التجريبي

150 mg (7-benzyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-2-yl)-phenyl-amine and 20 mg palladium on charcoal in 10 mL was stirred 1 day under 3 bar of a hydrogen atmosphere. The mixture was filtered and evaporated to yield 84 mg of the desired product. (M+H)+=241

المصدر