تفاعل #487437

ord-4b1bbf3a66324fc88b583320d996d174

معادلة التفاعل

O=[N+]([O-])c1ccc(-c2ccc(O)cc2)cc1
4'-hydroxy-(4-nitro biphenyl)
CC(C)N(C(=O)CBr)C(C)C
N,N-bis-(isopropyl)-2-bromo-acetamide
CC(C)N(C(=O)COc1ccc(-c2ccc([N+](=O)[O-])cc2)cc1)C(C)C
expected product
المردود 84.5%
CC(C)N(C(=O)COc1ccc(-c2ccc([N+](=O)[O-])cc2)cc1)C(C)C
N,N-bis-(isopropyl)-2[[4'-nitro-(1,1'-biphenyl)-4-yl]oxy]-acetamide
المردود 84.5%

الكواشف

لا شيء

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

The product was prepared as in Example 2, Stage A starting with 900 mg of 4'-hydroxy-(4-nitro biphenyl) (Aldrich) and 958 mg of N,N-bis-(isopropyl)-2-bromo-acetamide (Preparation 8) to obtain 1.26 g of the expected product.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US05827887uspto-grants-1998_10