تفاعل #48609

معادلة التفاعل

3,3-dimethylbutan-1-ol

vinyl acetate

sodium carbonate

→

title compound

3,3-Dimethyl-1-vinyloxybutane

المذيبات

benzene

ظروف التفاعل

المعالجة

1. 1
   أخرى12 hours
2. 2
   ترشيحfilter
3. 3
   workup.DISTILLATIONDistill the filtrate
4. 4
   أخرىcollect fraction
5. 5
   أخرىboiling ˜125° C.-130° C
6. 6
   أخرىFlush through a silica gel pad with hexanes
7. 7
   تركيزconcentrate

الإجراء التجريبي

Add chloro(1,5-cyclooctadiene)iridium(I) dimer (0.39 g, 0.59 mmol) to 3,3-dimethylbutan-1-ol (3.00 g, 29.35 mmol), vinyl acetate (10.11 g, 117.42 mmol) and sodium carbonate (1.87 g, 17.61 mmol) in benzene (10 mL) at room temperature. Boil under nitrogen 12 hours. Cool to room temperature and filter. Distill the filtrate and collect fraction boiling ˜125° C.-130° C. Flush through a silica gel pad with hexanes and concentrate to provide the title compound.

المصدر