تفاعل #4859

ord-49bfa957cdb54d11874d4d10e9a37feb

معادلة التفاعل

COC(=O)[C@@H](C)NC(=O)C(Cc1c(C)cc(O)cc1C)NC(=O)OC(C)(C)C
title compound
COC(=O)[C@@H](C)NC(=O)C(Cc1c(C)cc(O)cc1C)NC(=O)OC(C)(C)C
N-[(1,1-dimethylethoxy)carbonyl]-2,6dimethyl-DL-tyrosyl-D-alanine, methyl ester
→
Cc1cc(O)cc(C)c1C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@H](C)C(=O)O
title compound
Cc1cc(O)cc(C)c1C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@H](C)C(=O)O
N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-tyrosyl-D-alanine

المتفاعلات

COC(=O)[C@@H](C)NC(=O)C(Cc1c(C)cc(O)cc1C)NC(=O)OC(C)(C)C
title compound
COC(=O)[C@@H](C)NC(=O)C(Cc1c(C)cc(O)cc1C)NC(=O)OC(C)(C)C
N-[(1,1-dimethylethoxy)carbonyl]-2,6dimethyl-DL-tyrosyl-D-alanine, methyl ester

الكواشف

لا شيء

المذيبات

ClC(Cl)Cl
CHCl3

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

The title compound was prepared by the methods of Example 9 using diastereomer F of the title compound of Example 6. [α]D -21.7 (CHCl3)

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US04727189uspto-grants-1988_02