تفاعل #4855

معادلة التفاعل

2,3-dihydro-5,7-dinitro-2-methyl-benzofuran

methylamine

→

1-(2-methylamino-3,5-dinitrophenyl)-2-propanol

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةAfter the mixture is cooled
2. 2
   أخرىthe expected product precipitates
3. 3
   غسيلwashed with alcohol
4. 4
   أخرىrecrystallized from 50 ml of 96° strength ethanol
5. 5
   أخرىAfter being dried
6. 6
   أخرى0.047 mole (12 g) is obtained of a product which melts at 132° C.

الإجراء التجريبي

0.056 Mole (12.5 g) of 2,3-dihydro-5,7-dinitro-2-methyl-benzofuran is suspended in 100 ml of a 33% strength solution of methylamine in ethanol. After 10 hours' stirring at room temperature in a sealed Erlenmeyer, the reaction mixture is brought for 30 minutes to the refluxing temperature of the alcohol. After the mixture is cooled, the expected product precipitates. It is drained, washed with alcohol and then recrystallized from 50 ml of 96° strength ethanol. After being dried, 0.047 mole (12 g) is obtained of a product which melts at 132° C.

المصدر