تفاعل #48490

معادلة التفاعل

tetrabutylammonium di-tert-butyl phosphate

chloroiodomethane

→

di-tert-butyl chloromethyl phosphate

ظروف التفاعل

المعالجة

1. 1
   أخرىwere removed under vacuum
2. 2
   workup.ADDITION500 ml of ethyl ether was added to the residue and insoluble solid
3. 3
   ترشيحwas filtered away
4. 4
   أخرىConcentration of the filtrate in vacuo and removal of remaining volatiles

الإجراء التجريبي

A mixture of tetrabutylammonium di-tert-butyl phosphate (57 g, 0.126 mol, Digital Specialty Chemicals) and chloroiodomethane (221 g, 1.26 mol) was stirred at room temperature for four hours before the volatiles were removed under vacuum. 500 ml of ethyl ether was added to the residue and insoluble solid was filtered away. Concentration of the filtrate in vacuo and removal of remaining volatiles using a vacuum pump provided di-tert-butyl chloromethyl phosphate as a light brown or yellow oil, which was utilized in the next step without further purification.

المصدر