تفاعل #48358

معادلة التفاعل

2-Oxo-1-(1-benzylpiperidin-4-yl)-2,3-dihydro-1H-imidazo[4,5-b]pyrazine

hydrogen

→

title compound

المردود 124.4%

2-Oxo-1-(4-piperidinyl)-2,3-dihydro-1H-imidazo[4,5-b]pyrazine

المردود 124.4%

المذيبات

methanol

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe catalyst was filtered
2. 2
   أخرىsolvent evaporated

الإجراء التجريبي

2-Oxo-1-(1-benzylpiperidin-4-yl)-2,3-dihydro-1H-imidazo[4,5-b]pyrazine (1.7 g, 5.5 mmol) was dissolved in methanol (100 mL) and hydrogenated over 20% palladium on carbon (0.5 g) at 55 psi hydrogen overnight. The catalyst was filtered and solvent evaporated to give the title compound (1.5 g).

المصدر