تفاعل #48148
ord-774361b4ca9e4173a856bb1f7f466b42
معادلة التفاعل
[5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-morpholin-4-yl-methanone
intermediate 2
[5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-morpholin-4-yl-methanone
4-methoxyphenylboronic acid
→
title compound
[5-(1-Isopropyl-piperidin-4-yloxy)-1-(4-methoxy-phenyl)-1H-indol-2-yl]-morpholin-4-yl-methanone
المتفاعلات
الكواشف
لا شيء
ظروف التفاعل
الظروف التفصيلية
See reaction.notes.procedure_details.
المعالجة
- 1أخرىIn analogy to the procedure described for the synthesis of example 6
الإجراء التجريبي
In analogy to the procedure described for the synthesis of example 6, the title compound was synthesized from [5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-morpholin-4-yl-methanone (intermediate 2) and 4-methoxyphenylboronic acid. The title compound was obtained in 56% yield as yellow foam. MS (m/e): 478.2 (MH+, 100%).