تفاعل #48109

معادلة التفاعل

4-difluoromethyl-1-iodo-benzene

iPrMgCl

trimethyl borate

→

4-Difluoromethyl-phenylboronic acid

ظروف التفاعل

الإجراء التجريبي

In a departure from the procedure described above the compound is prepared from 4-difluoromethyl-1-iodo-benzene (prepared from 4-iodobenzaldehyde using diethylaminosulfurtrifluoride (DAST) in dichloromethane) using iPrMgCl to generate the arylmetal compound and trapping this intermediate with trimethyl borate.

المصدر