تفاعل #473925

معادلة التفاعل

{4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl]phenyl}methanol

→

4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl]benzaldehyde

المردود 80.4%

المذيبات

methylene chloride

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةthe mixture was then heated
2. 2
   ترشيحAfter filtration of the reaction mixture through Celite
3. 3
   تركيزthe resultant filtrate was concentrated under reduced pressure

الإجراء التجريبي

To a solution of {4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl]phenyl}methanol (1 g) in methylene chloride (30 mL), activated manganese oxide (1.8 g) was added, and the mixture was then heated and stirred for 3 hours at 40° C. After filtration of the reaction mixture through Celite, the resultant filtrate was concentrated under reduced pressure to yield 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl]benzaldehyde (0.8 g).

المصدر