تفاعل #4724

معادلة التفاعل

Hydrogen peroxide

N-methyl-N'-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-1,2-hydrazine dicarbothioamide

→

N-Methyl-N'-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]1,3,4-thiadiazole-2,5-diamine

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةthe reaction mixture is briefly heated to boiling
2. 2
   ترشيحThe sulphur which separates is filtered off hot with the aid of active charcoal
3. 3
   تركيزthe filtrate is concentrated by evaporation
4. 4
   أخرىpurified by preparative layer chromatography

الإجراء التجريبي

2 ml of 30% Hydrogen peroxide are added to 1.58 g (4 mmol) of N-methyl-N'-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-1,2-hydrazine dicarbothioamide in 30 ml of ethanol and the reaction mixture is briefly heated to boiling. The sulphur which separates is filtered off hot with the aid of active charcoal and the filtrate is concentrated by evaporation and purified by preparative layer chromatography.

المصدر