تفاعل #470387

معادلة التفاعل

N1-phenylbenzene-1,2-diamine

benzaldehyde

→

desired product

المردود 37.0%

1,2-diphenyl-1H-benzo[d]imidazole

المردود 37.0%

المذيبات

methoxylethanol

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةThe mixture was heated up
2. 2
   درجة الحرارةto reflux for 48 hours
3. 3
   أخرىthe solvent was evaporated
4. 4
   أخرىThe residue was purified by column chromatography

الإجراء التجريبي

N1-phenylbenzene-1,2-diamine (4.15 g, 22 mmol) and benzaldehyde (2.1 g, 20 mmol) were mixed with methoxylethanol (60 ml) in a three-neck flask. The mixture was heated up to reflux for 48 hours. After cooled to room temperature, the solvent was evaporated. The residue was purified by column chromatography using dichloromethane to 5% of ethyl acetate in dichloromethane as eluent. 2 g of desired product was obtained.

المصدر