تفاعل #4700

معادلة التفاعل

hydrazine hydrate

2-methyl-3-[3-(1-piperidinylmethyl)phenoxy]-1-propanamine

diphenylcarbonate

→

N-[2-Methyl-3-[3-(1-piperidinylmethyl)phenoxy]propyl]hydrazine carboxamide

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةthe reaction mixture is heated
2. 2
   درجة الحرارةunder reflux for one hour

الإجراء التجريبي

2.2 g (8 mmol) of 2-methyl-3-[3-(1-piperidinylmethyl)phenoxy]-1-propanamine in 20 ml of ethanol are stirred together with 1.9 g (8 mmol) of diphenylcarbonate at room temperature for 12 hours. 4 g of hydrazine hydrate is then added to the solution and the reaction mixture is heated under reflux for one hour. Isolation of the product is carried out as described in Example 1.

المصدر