تفاعل #46881

ord-bba2c92ab44f49fc867634839f0fdc10

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

4-[2-(tert-Butyl-dimethyl-silanyloxy)-ethoxy]-2-trichloromethyl-1H-benzoimidazole was prepared by a procedure according to example 108 (iii) starting from 503 mg (1.78 mmol) 3-[2-(tert-Butyl-dimethyl-silanyloxy)-ethoxy]-benzene-1,2-diamine and 0.31 mL (2.49 mmol) 2,2,2-trichloro-acetimidic acid methyl ester. Yield: 680 mg MS (ES+): m/e=409, chloro pattern.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US07741341B2uspto-grants-2010_06