تفاعل #46711

ord-ebd0374d9b3b4a19b59120cc38343070

معادلة التفاعل

CC(C)S(=O)(=O)NC1Cc2ccc(B3OC(C)(C)C(C)(C)O3)cc2C1
N-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide
CS(=O)(=O)Cc1cccc(Br)c1
(3-bromophenyl)methyl methyl sulfone
→
CC(C)S(=O)(=O)NC1Cc2ccc(-c3cccc(CS(C)(=O)=O)c3)cc2C1
title compound
CC(C)S(=O)(=O)NC1Cc2ccc(-c3cccc(CS(C)(=O)=O)c3)cc2C1
N-(5-{3-[(methylsulfonyl)methyl]phenyl}-2,3-dihydro-1H-inden-2-yl)-2-propanesulfonamide

المتفاعلات

CC(C)S(=O)(=O)NC1Cc2ccc(B3OC(C)(C)C(C)(C)O3)cc2C1
N-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide
CS(=O)(=O)Cc1cccc(Br)c1
(3-bromophenyl)methyl methyl sulfone

الكواشف

لا شيء

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

The title compound was prepared from N-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide and (3-bromophenyl)methyl methyl sulfone in a similar manner to Example 16.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US07741351B2uspto-grants-2010_06