تفاعل #466178

معادلة التفاعل

ethyl {4-[(2-guanidino-thiazole-5-carbonyl)-amino]-phenoxy}-acetate

hydrochloric acid

→

[4-[(2-guanidino-thiazole-5-carbonyl)-amino]-phenoxy]-acetic acid hydrochloride

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe precipitate is filtered off under suction
2. 2
   غسيلwashed with water
3. 3
   أخرىdried

الإجراء التجريبي

239 mg of ethyl {4-[(2-guanidino-thiazole-5-carbonyl)-amino]-phenoxy}-acetate are stirred for 27 hrs. in 4.8 ml of 25% hydrochloric acid. The precipitate is filtered off under suction, washed with water and dried. There are obtained 222 mg of [4-[(2-guanidino-thiazole-5-carbonyl)-amino]-phenoxy]-acetic acid hydrochloride (1:1), m.p. 336° C., MS: 364 (M+H)+.

المصدر