تفاعل #464215

معادلة التفاعل

3,5-diacetylaniline

4-Aminoacetophenone

trichloromethyl chloroformate

→

N-(4-acetylphenyl)-N'-(3,5-diacetylphenyl)urea

المذيبات

toluene

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةThe mixture was heated
2. 2
   درجة الحرارةat reflux for 2 hr
3. 3
   درجة الحرارةthe mixture was heated
4. 4
   درجة الحرارةat reflux for 1 hr
5. 5
   ترشيحThe product was filtered off
6. 6
   غسيلwashed with ethanol
7. 7
   أخرىdried

الإجراء التجريبي

4-Aminoacetophenone (1.35 g) in toluene (20 mL) was treated with trichloromethyl chloroformate (1.2 mL). The mixture was heated at reflux for 2 hr. 3,5-diacetylaniline (1.77 g) was added and the mixture was heated at reflux for 1 hr then allowed to stand 16 hr at room temp. The product was filtered off and washed with ethanol and dried to give 0.93 g of N-(4-acetylphenyl)-N'-(3,5-diacetylphenyl)urea, mp 251-2° C.

المصدر