تفاعل #462968

معادلة التفاعل

potassium hydroxide

2-hydroxybenzenesulfonamide

chlorotrifluoroethylene

→

title compound

المردود 60.7%

2-(2-Chloro-1,1,2-trifluoroethoxy)-benzenesulfonamide

المردود 60.7%

المذيبات

acetone

ظروف التفاعل

المعالجة

1. 1
   workup.STIRRINGAt 40° to 50° C. and while stirring
2. 2
   أخرىwas gassed in over a period of 12 hours
3. 3
   ترشيحThe precipitate was filtered off under such and
4. 4
   غسيلwashed with acetone
5. 5
   أخرىThe filtrate was evaporated down under reduced pressure
6. 6
   workup.STIRRINGstirred into 700 ml of water, suction
7. 7
   ترشيحfiltered
8. 8
   غسيلwashed
9. 9
   أخرىdried

الإجراء التجريبي

At 25 bis 30° C. and while stirring, 5.9 g (0.093 mol) of 88% strength potassium hydroxide powder was added over a period of 5 minutes to a solution of 28.4 g (0.164 Mol) of 2-hydroxybenzenesulfonamide in 200 ml of acetone. At 40° to 50° C. and while stirring, 29.6 g (0.254 mol) of chlorotrifluoroethylene was gassed in over a period of 12 hours. The precipitate was filtered off under such and washed with acetone. The filtrate was evaporated down under reduced pressure, stirred into 700 ml of water, suction filtered, washed and dried. There was obtained 28.8 g (60.7%) of the title compound of m.p. 113° to 116° C.

المصدر