تفاعل #461775

معادلة التفاعل

caproyl chloride

n-pentylamine

→

N-Pentyl-caproamide

المذيبات

methylene chloride

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةwhile cooling with ice
2. 2
   غسيلthe reaction solution is washed in succession with 11 of 0.1N HCl, 11 of 0.1N NaOH and 1.51 of NaCl solution
3. 3
   تركيزThe organic phase is concentrated on a rotary evaporator
4. 4
   أخرىdried in a high vacuum
5. 5
   أخرىgives 370 g of a crystalline mass (98% of theory)

الإجراء التجريبي

275 g of caproyl chloride are added dropwise within 30 minutes to a solution of 500 ml of n-pentylamine in 1.41 of methylene chloride while cooling with ice and stirring. After standing at room temperature for 4 hours the reaction solution is washed in succession with 11 of 0.1N HCl, 11 of 0.1N NaOH and 1.51 of NaCl solution. The organic phase is concentrated on a rotary evaporator and dried in a high vacuum and gives 370 g of a crystalline mass (98% of theory). M.p. 37° C.

المصدر