تفاعل #461472

معادلة التفاعل

5-[2,5-dimethyl-4-(phenylmethoxy)phenoxy]-2,2-dimethylpentanoic acid, methyl ester

5-[2,5-Dimethyl-4-(phenylmethoxy)phenoxy]-2,2-dimethylpentanoic acid, methyl ester

→

title compound

المردود 107.0%

5-(4-Hydroxy-2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid, methyl ester

المردود 107.0%

المذيبات

methanol

ظروف التفاعل

المعالجة

1. 1
   أخرىThe catalyst is removed
2. 2
   أخرىthe solvent is evaporated

الإجراء التجريبي

A solution of 1.85 g (5 mmol) of 5-[2,5-dimethyl-4-(phenylmethoxy)phenoxy]-2,2-dimethylpentanoic acid, methyl ester (Example 13) in 100 mL of methanol and 0.2 g of 20% palladium on carbon is shaken under a hydrogen atmosphere of 50 pounds per square inch (psi) for 14 hours. The catalyst is removed and the solvent is evaporated to afford the title compound as a colorless oil (1.5 g).

المصدر