تفاعل #4583

معادلة التفاعل

3-chloroperbenzoic acid

2-allyloxyphenylsulfonamide

→

2-oxiranylmethoxyphenylsulfonamide

المردود 78.0%

المذيبات

methylene chloride

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةThe solution is then heated
2. 2
   درجة الحرارةto reflux for 3 hours
3. 3
   درجة الحرارةcooled
4. 4
   غسيلwashed three times with saturated sodium carbonate solution
5. 5
   أخرىThe organic phase is dried
6. 6
   تركيزconcentrated

الإجراء التجريبي

To a mixture of 15.3 g of 3-chloroperbenzoic acid in 270 ml of absolute methylene chloride are added 14.2 g of 2-allyloxyphenylsulfonamide over 2 minutes. The solution is then heated to reflux for 3 hours, cooled, and then washed three times with saturated sodium carbonate solution and once with water. The organic phase is dried and concentrated, affording 11.9 g of 2-oxiranylmethoxyphenylsulfonamide with a melting point of 132°-133° C.

المصدر