تفاعل #456264

معادلة التفاعل

4,4,4-trifluoro-1-(6-chlorobenzothiazol-2-yl)butane-1,3-dione

4-sulfamoylphenylhydrazine hydrochloride

→

4-[5-(6-chlorobenzothiazol-2-yl)-3-trifluoromethyl-1H-pyrazol-1-yl]benzenesulfonamide

ظروف التفاعل

الإجراء التجريبي

The procedure of Example 9 was repeated using 4,4,4-trifluoro-1-(6-chlorobenzothiazol-2-yl)butane-1,3-dione and 4-sulfamoylphenylhydrazine hydrochloride as the starting materials to obtain 4-[5-(6-chlorobenzothiazol-2-yl)-3-trifluoromethyl-1H-pyrazol-1-yl]benzenesulfonamide. NMR(CDCl3 -DMSO-d6) δ: 6.91 (2H, bs), 7.30-7.49 (2H, m), 7.63 (2H, d, J=8.9 Hz), 7.88-7.91 (2H, m), 8.05 (2H, d, J=8.9 Hz); mp 254-255° C. (ethanol)

المصدر