تفاعل #452416

معادلة التفاعل

n-heptyl bromide

NaHCO3

m-aminophenol

→

3-(n-heptyl-amino)phenol

المردود 62.0%

المذيبات

methanol

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةthe mixture is refluxed for 5 h
2. 2
   درجة الحرارةAfter cooling
3. 3
   ترشيحit is filtered
4. 4
   أخرىthe solvent is removed in vacuo

الإجراء التجريبي

0.11 mol of n-heptyl bromide and 0.1 mol of NaHCO3 are added to 0.1 mol of m-aminophenol in 150 ml of methanol, and the mixture is refluxed for 5 h. After cooling, it is filtered and the solvent is removed in vacuo. The oil which remains is fractionated in vacuo, to give 3-(n-heptyl-amino)phenol.

المصدر