تفاعل #44875

معادلة التفاعل

tert-butyl [(4-hydroxypiperidin-4-yl)methyl]carbamate

methyl 1-(iodomethyl)cyclohexanecarboxylate

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title compound

Methyl 1-[(4-{[(tert-butoxycarbonyl)amino]methyl}-4-hydroxypiperidine-1-yl)methyl]cyclohexanecarboxylate

ظروف التفاعل

الإجراء التجريبي

The title compound was prepared by a method similar to that shown in the Step 2 of Example 3 by using tert-butyl [(4-hydroxypiperidin-4-yl)methyl]carbamate (Chem. Pharm. Bull., 2002, 50 (9) 1187-1194) and methyl 1-(iodomethyl)cyclohexanecarboxylate (Step 1 of Example 6).

المصدر