تفاعل #4473

معادلة التفاعل

product

1,3-Cyclohexanedione mono(4-bromophenylhydrazone)

water

→

title compound

6-Bromo-1,2,3,9-tetrahydro-4H-carbazol-4-one

المذيبات

acetic acid

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةThe mixture was cooled
2. 2
   ترشيحthe resulting solid filtered off
3. 3
   أخرىdried (0.95 g)
4. 4
   أخرىPurification by flash chromatography (E)

الإجراء التجريبي

The product of Stage (i) (1.5 g) was heated under reflux with dry zinc chloride (16 g) in glacial acetic acid (75 ml) for 24 h. The mixture was cooled, poured into water (200 ml), and the resulting solid filtered off and dried (0.95 g). Purification by flash chromatography (E) gave the title compound as a solid (125 mg). T.l.c. (F), Rf 0.65

المصدر