تفاعل #44703

معادلة التفاعل

2-amino-4,6-dichloropyrimidine

4-aminobenzonitrile

hydrochloric acid

→

4-[(2-Amino-6-chloropyrimidin-4-yl)amino]benzonitrile

المذيبات

water

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe precipitate is filtered off with suction

الإجراء التجريبي

300 mg (1.83 mmol) of 2-amino-4,6-dichloropyrimidine and 216 mg (1.83 mmol) of 4-aminobenzonitrile are suspended in 6 ml of water. 180 μl of concentrated hydrochloric acid are added, and the mixture is stirred at 100° C. overnight. The precipitate is filtered off with suction.

المصدر