تفاعل #44369

ord-f89d528f07aa40eab0876808d4b23adb

معادلة التفاعل

C[C@@H]1CCC[C@H](C)N1C(=O)c1ccc(-c2cc(Cl)ccc2OCC(=O)O)cc1Cl
product
C[C@@H]1CCC[C@H](C)N1C(=O)c1ccc(-c2cc(Cl)ccc2OCC(=O)O)cc1Cl
[[3′,5-dichloro-4′-[[(2R,6S)-2,6-dimethyl-1-piperidinyl]carbonyl][1,1′-biphenyl]-2-yl]oxy]-acetic acid
CC1CCCN1
2-methylpyrrolidine
COc1ccc(Cl)cc1-c1ccc(C(=O)N2CCCC2C)c(Cl)c1
sub-title compound
COc1ccc(Cl)cc1-c1ccc(C(=O)N2CCCC2C)c(Cl)c1
1-[(3,5′-dichloro-2′-methoxy[1,1′-biphenyl]-4-yl)carbonyl]-2-methyl-pyrrolidine

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

The sub-title compound was prepared by the method of example 18 step a) using the product of step example 21 step a) and 2-methylpyrrolidine.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US07737135B2uspto-grants-2010_06