تفاعل #44146

معادلة التفاعل

(5-bromo-2-fluorophenyl)acetaldehyde

2-methyl-5-(1-piperazinyl)quinoline

sodium triacetoxyborohydride

→

title compound

المردود 95.0%

5-{4-[2-(5-Bromo-2-fluorophenyl)ethyl]-1-piperazinyl}-2-methylquinoline

المردود 95.0%

ظروف التفاعل

الإجراء التجريبي

The title compound was prepared in 95% yield from (5-bromo-2-fluorophenyl)acetaldehyde (0.98 g), 2-methyl-5-(1-piperazinyl)quinoline (0.51 g) and sodium triacetoxyborohydride (0.95 g) according to the procedure described for Example 131.

المصدر